Of Two Make One: The Biosynthesis of Phenazines

Matthias Mentel; Ekta G. Ahuja; Dmitri V. Mavrodi; Rolf Breinbauer; Linda S. Thomashow; Wulf Blankenfeldt

doi:10.1002/cbic.200900323

Of Two Make One: The Biosynthesis of Phenazines

Matthias Mentel
, Ekta G. Ahuja
, Dmitri V. Mavrodi
, Rolf Breinbauer
, Linda S. Thomashow
, Wulf Blankenfeldt^*

^*Corresponding author for this work

Institute of Organic Chemistry (6410)

Research output: Contribution to journal › Article › peer-review

Abstract

Five easy steps: Phenazines are redox-active bacterial secondary metabolites that possess broad-specificity antibiotic activity and can also play an important role as virulence factors in infectious disease. Their biosynthesis from two molecules of chorismic acid is catalyzed by enzymes encoded in the conserved phz operon.

Original language	English
Pages (from-to)	2295-2304
Journal	ChemBioChem
Volume	10
Issue number	14
DOIs	https://doi.org/10.1002/cbic.200900323
Publication status	Published - 2009

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This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1002/cbic.200900323

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@article{31797847c2294c08a758f04f3f0bd8ec,

title = "Of Two Make One: The Biosynthesis of Phenazines",

abstract = "Five easy steps: Phenazines are redox-active bacterial secondary metabolites that possess broad-specificity antibiotic activity and can also play an important role as virulence factors in infectious disease. Their biosynthesis from two molecules of chorismic acid is catalyzed by enzymes encoded in the conserved phz operon. ",

author = "Matthias Mentel and Ahuja, \{Ekta G.\} and Mavrodi, \{Dmitri V.\} and Rolf Breinbauer and Thomashow, \{Linda S.\} and Wulf Blankenfeldt",

year = "2009",

doi = "10.1002/cbic.200900323",

language = "English",

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AU - Mentel, Matthias

AU - Ahuja, Ekta G.

AU - Mavrodi, Dmitri V.

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AU - Thomashow, Linda S.

AU - Blankenfeldt, Wulf

PY - 2009

Y1 - 2009

N2 - Five easy steps: Phenazines are redox-active bacterial secondary metabolites that possess broad-specificity antibiotic activity and can also play an important role as virulence factors in infectious disease. Their biosynthesis from two molecules of chorismic acid is catalyzed by enzymes encoded in the conserved phz operon.

AB - Five easy steps: Phenazines are redox-active bacterial secondary metabolites that possess broad-specificity antibiotic activity and can also play an important role as virulence factors in infectious disease. Their biosynthesis from two molecules of chorismic acid is catalyzed by enzymes encoded in the conserved phz operon.

U2 - 10.1002/cbic.200900323

DO - 10.1002/cbic.200900323

M3 - Article

SN - 1439-7633

VL - 10

SP - 2295

EP - 2304

JO - ChemBioChem

JF - ChemBioChem

IS - 14

ER -

Of Two Make One: The Biosynthesis of Phenazines

Abstract

UN SDGs

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