Research output per year
Research output per year
Personal profile
Austrian Fields of Study 2012 (6-stellig)
- 106002 Biochemistry
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Dive into the research topics where Horst Lechner is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Computational enzyme design by catalytic motif scaffolding
Braun, M., Tripp, A., Chakatok, M., Kaltenbrunner, S., Fischer, C., Stoll, D., Bijelic, A., Elaily, W., Totaro, M. G., Moser, M., Hoch, S. Y., Lechner, H., Rossi, F., Aleotti, M., Hall, M. & Oberdorfer, G., 1 Jan 2026, In: Nature. 649, p. 237-245 9 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Computational design of highly active de novo enzymes
Braun, M., Tripp, A., Chakatok, M., Kaltenbrunner, S., Fischer, C., Stoll, D., Bijelic, A., Elaily, W., Totaro, M. G., Moser, M., Hoch, S. Y., Lechner, H., Rossi, F., Aleotti, M., Hall, M. & Oberdorfer, G., 12 Jun 2025, bioRxiv.Research output: Working paper › Preprint
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Click, Compute, Create: A Review of Web-based Tools for Enzyme Engineering
Tripp, A., Braun, M., Wieser, F., Oberdorfer, G. & Lechner, H., 16 Oct 2024, In: ChemBioChem. 25, 20, 19 p., e202400092.Research output: Contribution to journal › Review article › peer-review
Open AccessFile -
Computational design of a thermostable de novo biocatalyst for whole cell biotransformations
Elaily, W., Stoll, D., Chakatok, M., Aleotti, M., Grill, B., Lechner, H., Hall, M. & Oberdorfer, G., 7 Oct 2024, bioRxiv.Research output: Working paper › Preprint
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De novo design of a multifunctional thermostable protein catalyst with a novel fold
Elaily, W., Oberdorfer, G., Grill, B., Lechner, H., Braun, M. & Hall, M., 19 Apr 2023.Research output: Contribution to conference › Poster
Activities
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Kinderuni - Workshop - "Alles Leben ist Chemie"
Lechner, H. (Speaker), Trenker-El-Toukhy, R. (Organiser), Frießer, E. M. (Contributor), Schrüfer, A. C. (Speaker), Pelzmann, P. (Speaker), Schaffer, C. (Speaker), Baldauf, S. (Speaker), Moser, M. (Speaker), Haas, T. (Speaker) & Knees, M. (Speaker)
12 Feb 2026Activity: Public engagement › Schools engagement
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Computational Design of New Proteases
Kolathuparambil, S. (Speaker) & Lechner, H. (Contributor)
30 Sept 2025Activity: Talk or presentation › Poster presentation › Science to science
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Developing Machine-Learning-Driven Sequence Design Strategies to Stabilize and Produce Challenging Enzymes
Lechner, H. (Speaker), Kolathuparambil, S. (Contributor) & Alagic, A. (Contributor)
20 Mar 2025Activity: Talk or presentation › Poster presentation › Science to science
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Enhancing Recombinant Protein Expression Yields through Machine Learning-Based Sequence Design
Lechner, H. (Speaker), Alagic, A. (Contributor), Oberdorfer, G. (Contributor), Macheroux, P. (Contributor), Braun, M. (Contributor), Baldauf, S. (Contributor), Cohen Hoch, D. (Contributor), Sojer, C. (Contributor) & Almeida Freitas, P. D. (Contributor)
30 Jun 2025Activity: Talk or presentation › Poster presentation › Science to science
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De novo design of a Michealase by simultaneous catalytic array scaffolding and substrate affinity optimization
Stoll, D. (Speaker), Tripp, A. (Contributor), Braun, M. (Contributor), Ferruz, N. (Contributor), Oberdorfer, G. (Contributor) & Lechner, H. (Contributor)
21 Oct 2025Activity: Talk or presentation › Poster presentation › Science to science
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FWF - ENHANCENZPROD - Yield enhancement of recombinant enzyme production
Lechner, H. (Project manager on research unit)
1/11/25 → 31/01/29
Project: Research project
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FWF - ArtEnzDes - Design of Artificial Enzymes for the Baylis-Hillman reaction
Lechner, H. (Project manager on research unit)
1/08/20 → 31/12/20
Project: Research project